The distinct aging rates of neural progenitor cells and Wnt signaling dictate mammalian cortical layer proportions.

Biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new 'gene atlas' with 4-D imaging, the researchers ...

The role of Fibroblast Growth Factor 8 (FGF8) in embryonic development and organ formation is gaining increased recognition as scientists uncover its wide-ranging influence. FGF8, a powerful signaling ...

A discovery upends decades of assumptions regarding DNA replication. The study show that DNA replication in early embryos is different from what past research has taught, and includes a period of ...

Embryo organoids made from stem cells are enabling scientists to recreate early pregnancy in the lab, unlocking treatments ...

For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...

The team observed the emergence of the three-dimensional embryo-like structures under a microscope in the lab. These started producing blood (seen here in red) after around two weeks of development - ...

Paired box 6 (PAX6) is a member of the highly conserved paired box (PAX) transcription factors. Transcription factors regulate the activity of large numbers of genes involved in development. The PAX6 ...